Viral Sensitizers Unleash Host Cell Potential to Enhance AAV Production

Poster highlights a collaborative study between Virica Biotech and FUJIFILM Irvine Scientific demonstrating how Viral Sensitizers (VSE™) enhance AAV production by transiently suppressing innate cellular defenses. Through screening and validation in Expi293F cells, VSEs were shown to significantly increase AAV2, AAV5, and AAV8 yields across the various serotypes in shake flask and Ambr15 studies. Easily integrated as a media additive, VSEs are rapidly metabolized by the producer cells and cleared by standard purification methods, making them a seamless solution to improve viral vector productivity without impacting your current process.